Thyrox 50 mg. Tablets || Price, Generic, Dosage, and all

• Generic name:  Levothyroxine Sodium 
• Manufacturing Company:  Renata Limited.

The price of Thyrox 50 mg  

• Per piece: 2.20 Tk
• Strip: 66Tk (30 tablets)
• Box: 198Tk (30*3 Tablets)

The thyroid gland does not produce enough thyroid hormone, a condition known as hypothyroidism, for which Thyrox is a medication. It is a synthetic form of the thyroid hormone T4, which helps regulate metabolism, growth, and development. Thyrox works by replacing the thyroid hormone that your body is not producing. This helps to regulate your metabolism and other important bodily functions. The dosage of Thyrox will vary depending on your individual needs. It is important to follow your doctor’s instructions carefully. You typically take Thyrox as a tablet once a day, usually in the morning on an empty stomach. Overall, Thyrox is a safe and effective medication for the treatment of hypothyroidism. It’s important to follow your doctor’s orders and monitor your condition.  

Alternative medicine 

There are many alternative medicines of Thyrox 50 mg available in the market from different companies, they are:  

SL	alternative medicine	Manufacturing company	Price
1.	Thyrin 50mg	Square Pharmaceuticals Ltd	2.25 Tk
2.	Thyronor 50mg	Nuvista Pharma Limited.	2.02 Tk
3.	Thyrolar 50mg	ACME Laboratories Ltd.	1.20 Tk
4.	Synroid 50mg	Beximco Pharmaceuticals Ltd.	1.60 Tk
5.	Thynor 50mg	Eskayef Bangladesh Ltd	2 Tk

Indications | Thyrox 50 mg  

Drug interactions with Thyrox

• Tri/tetracyclic antidepressants: Concurrent use may increase the therapeutic and toxic effects of both drugs.
• Sertraline may lead to increased Thyrox requirements in stabilised patients.
• Antidiabetic agents or insulin may increase the need for these medications when starting, changing, or discontinuing Thyrox therapy.
• Digitalis glycosides: When a patient transitions from hypothyroidism to euthyroidism, serum levels may decrease.

It is important to inform your doctor about all other medications you are taking to avoid potential drug interactions.

Pharmacology Thyrox 50

The thyroid gland produces the natural thyroid hormone T4, which is identical to the synthetic form of the thyroid hormone, Thyrox 50 mg. People use it to treat hypothyroidism, a condition where the thyroid gland fails to produce enough thyroid hormone. Thyrox 50 mg works by replacing the missing thyroid hormone, helping to regulate metabolism, growth, and development. It is typically taken orally once a day, and the dosage is adjusted based on individual needs.  

Dosage and Administration

Adult Dosage:

• Initial Starting Dose: 25-50 mcg/day
• Dose Adjustments: Increase gradually by 12.5-25 mcg every 6-8 weeks, as needed, until TSH levels normalize and the patient is clinically euthyroid.  

Specific Conditions:

• Severe Hypothyroidism: Start with 12.5-25 mcg/day and increase by 25 mcg every 2-4 weeks.  
• Secondary or Tertiary Hypothyroidism: Titrate until clinically euthyroid and serum free T4 is in the upper normal range.  
• Older Adults or Patients with Cardiac Disease: 1.7 mcg/kg/day.

Pediatric Dosage:

• Newborns: 10-15 mcg/kg/day, lower for those at risk of cardiac failure.
• Infants and Children: Adjust dosage based on age and severity of hypothyroidism. Refer to specific guidelines for age-appropriate ranges.

Important Considerations:

• Individualization: Dosage may vary based on individual response and laboratory parameters.
• Monitoring: Regular clinical and laboratory assessments are necessary to adjust dosage as needed.  
• Consult a Doctor: Always consult your doctor for personalized dosage recommendations.

Note: This information is for general guidance. It is essential to follow your doctor’s specific instructions for your individual situation.  

Drug interactions

Thyrox may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Some examples include:

• Tricyclic antidepressants and tetracyclic antidepressants: Concurrent use may increase the therapeutic and toxic effects of both drugs.
• Sertraline: May result in increased Thyrox requirements in stabilized patients.
• Antidiabetic agents or insulin: May increase the need for these medications when Thyrox therapy is started, changed, or discontinued.
• Digitalis glycosides: Serum levels may be reduced in hyperthyroidism or when a hypothyroid patient becomes euthyroid.

It is crucial to inform your doctor about all other medications you are taking to avoid potential drug interactions and ensure the safe and effective use of Thyrox.

Side effects  

Thyrox, a medication used to treat thyroid hormone deficiency, is generally well tolerated, but like all medications, it may cause some side effects in certain individuals. Common side effects include increased heart rate (tachycardia), nervousness, irritability, and difficulty sleeping (insomnia). In some cases, patients may experience headaches, weight loss, sweating, and diarrhea. Rare but serious side effects could include chest pain, shortness of breath, or signs of allergic reactions like rashes, swelling, or difficulty breathing.

If any severe side effects are observed, it is important to contact a healthcare professional immediately.

Use during pregnancy and lactation 

Thyrox (levothyroxine) is considered safe for use during pregnancy, as maintaining normal thyroid hormone levels is essential for the health of both the mother and the developing fetus. It is crucial to continue treatment for hypothyroidism during pregnancy, but regular monitoring and possible dose adjustments are recommended, as thyroid hormone needs may increase.

During lactation, Thyrox is also considered safe, as only small amounts of the drug pass into breast milk. However, the infant should still be monitored for any potential effects. Always consult with a healthcare provider to ensure proper dosage and monitoring during pregnancy and breastfeeding.

Guidance 

• Dosage: Follow your doctor’s instructions; don’t change doses on your own.
• Timing: Take on an empty stomach, 30-60 minutes before breakfast.
• Consistency: Take at the same time daily.
• Interactions: Avoid antacids, calcium, or iron within 4 hours of Thyrox.
• Monitoring: Regular blood tests are needed to adjust the dose.
• Missed Dose: Take it when remembered, but skip if it’s close to the next dose.
• Long-term: Thyrox is usually a lifelong medication, so consistency is key.
• Consult Doctor: Always consult before making changes, especially if pregnant or facing side effects.

Overdose effects

Overdose symptoms are similar to those of hyperthyroidism and may include agitation, confusion, irritability, hyperactivity, headache, sweating, dilated pupils, rapid heartbeat, irregular heart rhythms, rapid breathing, fever, increased bowel movements, and seizures. In severe cases, cerebral embolism, shock, coma, or even death have been reported. Symptoms may not appear immediately and could take several days to develop. If signs of overdose occur, the dose of Thyrox should be reduced or temporarily stopped. Treatment is symptomatic, addressing the specific symptoms.

Therapeutic classes 

Therapeutic classes are: Thyroid drugs & hormone

Warning | Thyrox 50 

• Untreated subclinical or overt Thyrotoxicosis of any etiology
• Acute Myocardial Infarction
• Uncorrected Adrenal failure.

Chemical Composition

Chemical Formula: C15H11I4NO4

Chemical Stucture: 

Storage Conditions

Store below 30°C and dry place, protect from light. Keep out of the reach of children.

***Special announcement

Although we have carefully gathered the information from various sources, you should not use it as a substitute for medical advice. Always consult a doctor before using any medication. Our source-based information cannot be guaranteed to be effective or useful. Therefore, the above-mentioned information does not hold us responsible for any side effects that may occur after taking the medicine.

• This information is for general information only and is in no way a substitute for medical advice.

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Thyrox 50 mg – FAQs 

 1. What is Thyrox used for?

Thyrox is used as a replacement therapy for hypothyroidism (underactive thyroid) and for the suppression of Thyroid Stimulating Hormone (TSH) levels in goitres, nodules, and after treatment for thyroid cancer.

2. How does Thyrox work?

Thyrox contains Levothyroxine, a synthetic form of the thyroid hormone T4, which the body converts into the active hormone T3. This helps regulate metabolism and energy production.

3. What is the recommended dosage of Thyrox for adults?

The initial adult dosage is typically 25-50 mcg/day, with gradual increases every 6-8 weeks based on clinical needs. For severe hypothyroidism, the starting dose is 12.5-25 mcg/day.

4. Is Thyrox safe for children?

Yes, Thyrox is safe for children. The dosage is adjusted based on age and body weight, with specific guidelines provided for infants and older children.

5. Can Thyrox be taken during pregnancy?

Yes, Thyrox is safe during pregnancy, and it may be necessary to increase the dosage to meet the higher thyroid hormone demands of pregnancy.

6. Can I take Thyrox while breastfeeding?

Thyrox is excreted minimally in breast milk, but it is generally considered safe for breastfeeding mothers. However, thyroid hormone levels should be carefully monitored.

7. What should I do if I miss a dose of Thyrox?

If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue your regular schedule. Do not double up.

8. What are the common side effects of Thyrox?

Common side effects include fatigue, increased appetite, weight loss, heat intolerance, sweating, headaches, nervousness, tremors, and palpitations.

9. Can I take other medications with Thyrox?

Thyrox can interact with certain medications such as antidepressants, insulin, and digoxin. It’s important to inform your doctor about all medications you’re taking.

10. What happens if I overdose on Thyrox?

Overdosing on Thyrox can lead to symptoms of hyperthyroidism like agitation, confusion, sweating, rapid heartbeat, and in severe cases, coma or death. If an overdose occurs, seek medical attention immediately.

11. Are there any contraindications for using Thyrox?

Thyrox should not be used in patients with untreated thyrotoxicosis, acute myocardial infarction, or uncorrected adrenal failure.

12. Can Thyrox be used for weight loss?

No, Thyrox should not be used for weight loss. Misuse of Thyrox for this purpose can result in serious health risks, including heart problems and hyperthyroidism.

13. How should I store Thyrox?

Store Thyrox in a cool, dry place below 30°C, away from light. Keep it out of the reach of children.

14. How long does Thyrox take to work?

It may take several weeks for Thyrox to fully regulate thyroid hormone levels and for symptoms of hypothyroidism to improve.

15. Can I stop taking Thyrox once I feel better?

No, do not stop taking Thyrox without consulting your doctor. Thyroid hormone replacement therapy is usually a lifelong treatment for hypothyroidism.

reference

• Company: https://renata-ltd.com/product/thyrox-tablet/ 
• USP: https://store.usp.org/product/1365000 
• Generic: https://en.wikipedia.org/wiki/Levothyroxine