Rosuva 10 mg. Tablets || Price, Generic, Dosage, and all information 

• Generic Name: Rosuvastatin Calcium
• Manufacturing Company:  Square Pharmaceuticals Ltd.

The price Rosuva 10mg  

• Per piece: 20 Tk
• Stript: 201.30 Tk (10 tablets)
• Box: 603.90 Tk(10*3 Tablets)

Rosuva 10 mg Tablet is a medication classified as an HMG-CoA reductase inhibitor, commonly known as a statin. It is primarily used to lower cholesterol and triglyceride levels in the body, making it effective for managing conditions such as hyperlipidemia, hypertriglyceridemia, type 3 hyperlipoproteinemia, and the prevention of stroke. While generally considered safe, users may experience side effects, including muscle pain, weakness, headaches, and abdominal discomfort. It is essential to follow your doctor’s instructions regarding the duration of use and dosage. Lifestyle modifications, such as adhering to a low-cholesterol diet and engaging in regular exercise, are recommended for optimal results. Patients should also be aware of potential interactions with alcohol and other medications, and it is crucial to monitor liver function and blood sugar levels regularly during treatment.

Alternative medicine 

There are many alternatives to Rosuva 10 available in the market from different companies, some of them are:  

Sl:	alternative	Manufacturing company	Price
1.	Rovast 10	Healthcare Pharmaceuticals Ltd	10 Tk
2.	Rosu 10	Popular Pharmaceuticals Ltd	11.25 Tk
3.	Rocovas 10	Incepta Pharmaceuticals Ltd	10 Tk
4.	Rostatin 10	Drug International Ltd	11.20 Tk
5.	RTV	Delta Pharma Ltd	5 Tk

Indications | Rosuva 10 

Rosuva 10 mg Tablet is primarily indicated for the following conditions:

• Hyperlipidemia: It helps lower elevated cholesterol levels in the blood, particularly LDL (low-density lipoprotein) cholesterol, which is often referred to as “bad” cholesterol.
• Hypertriglyceridemia: This medication is effective in reducing high triglyceride levels, which can contribute to cardiovascular disease.
• Type 3 Hyperlipoproteinemia: Rosuva is used to manage this condition characterized by abnormal lipid levels in the blood.
• Prevention of Cardiovascular Events: It may be prescribed to reduce the risk of heart attacks, strokes, and other cardiovascular complications in patients with established heart disease or those at high risk.
• Familial Hypercholesterolemia: Rosuva can be used in individuals with this genetic disorder that leads to high cholesterol levels, requiring aggressive treatment to manage lipid profiles.

Always consult a healthcare provider for personalized recommendations and to ensure the medication is appropriate for your specific health condition. 

Pharmacology Rosuva 10

Rosuva 10 mg Tablet contains Rosuvastatin, a selective HMG-CoA reductase inhibitor that reduces cholesterol production in the liver. By lowering LDL (low-density lipoprotein) and triglycerides, it helps improve the lipid profile and decrease the risk of cardiovascular diseases.

After oral administration, Rosuvastatin reaches peak plasma concentrations within 3 to 5 hours and has about 20% bioavailability. It is highly protein-bound (approximately 88%) and primarily excreted unchanged in the feces. The drug undergoes minimal metabolism through the cytochrome P450 system (CYP2C9), with an elimination half-life of around 19 hours, allowing for once-daily dosing.

Rosuvastatin is indicated for conditions like hyperlipidemia, hypertriglyceridemia, and familial hypercholesterolemia, often in conjunction with dietary changes and lifestyle modifications. Always consult a healthcare professional for personalized advice regarding treatment with Rosuvastatin.

Dosage and Administration  

Dosage and Administration of Rosuvastatin

Pediatric Patients (10 to 17 years):

• Usual dose: 5-20 mg/day
• Maximum dose: 20 mg/day
• Doses should be individualized based on therapy goals.
• Adjustments: At intervals of 4 weeks or more.

Very High Cholesterol & High Risk of Myocardial Infarction or Stroke:

• Recommended dose: 40 mg once daily

Homozygous Familial Hypercholesterolemia:

• Starting dose: 20 mg once daily.
• Response should be estimated from preapheresis LDL-C levels.

Asian Patients:

• Initiate therapy: 5 mg once daily.

Use with Cyclosporine, Lopinavir/Ritonavir, or Atazanavir/Ritonavir:

• Cyclosporine: Limit to 5 mg once daily.
• Lopinavir/Ritonavir or Atazanavir/Ritonavir: Limit to 10 mg once daily.

Concomitant Lipid-Lowering Therapy:

• Caution with Niacin or Fenofibrate: Consider reducing Rosuvastatin dosage.
• Avoid combination with Gemfibrozil; if necessary, limit Rosuvastatin to 10 mg once daily.

Severe Renal Impairment:

• Starting dose: 5 mg once daily.
• Maximum dose: 10 mg once daily for patients not on hemodialysis. 

Drug interactions Rosuva 10

Rosuvastatin may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Some notable drug interactions include:

• Cyclosporine: Combining Rosuvastatin with Cyclosporine can increase Rosuvastatin exposure. If used together, the Rosuvastatin dose should be limited to 5 mg once daily.
• Gemfibrosil: The combination of Rosuvastatin with Gemfibrosil should be avoided due to the increased risk of muscle damage. If used together, the Rosuvastatin dose should be limited to 10 mg once daily.
• Lopinavir/Ritonavir or atazanavir/ritonavir: These HIV protease inhibitors can increase Rosuvastatin exposure. The Rosuvastatin dose should be limited to 10 mg once daily if used in combination.  
• Coumarin anticoagulants: Using Rosuvastatin with coumarin anticoagulants can prolong the international normalized ratio (INR), increasing the risk of bleeding. A stable INR should be achieved before starting Rosuvastatin, and INR should be monitored frequently during and after initiating or adjusting Rosuvastatin therapy.
• Concomitant lipid-lowering therapies: Using Rosuvastatin with fibrates or niacin products may increase the risk of muscle effects, such as myopathy or rhabdomyolysis.

It is important to inform your doctor about all other medications you are taking to avoid potential drug interactions. 

Side effects Rosuva 10  

Rosuvastatin 10 mg, like other statin medications, can cause some side effects. While most side effects are mild, such as muscle aches, headache, nausea, and digestive issues, some may be more serious. In rare cases, Rosuvastatin can cause muscle breakdown, which can lead to kidney damage and muscle weakness. If you experience any unusual symptoms, such as muscle pain, tenderness, or weakness, especially if accompanied by fever or dark urine, it is important to seek medical attention immediately.

It is important to note that not everyone will experience side effects, and the severity of side effects can vary. If you experience any side effects that are bothersome or persistent, please talk to your doctor. 

Use during pregnancy and lactation 

Pregnancy:

• Avoid use: Rosuvastatin should generally be avoided in women of childbearing age unless there is a compelling need and the patient is highly unlikely to become pregnant.
• Discontinue if pregnant: If pregnancy occurs while taking Rosuvastatin, the medication should be discontinued immediately.

Breastfeeding:

• Limited data: Although limited data is available, a small amount of another drug in the same class as Rosuvastatin has been found to pass into breast milk.
• Weigh risks and benefits: If breastfeeding is necessary, the potential risks and benefits of Rosuvastatin use should be carefully evaluated by a healthcare provider.

It is important to consult with your doctor before taking Rosuvastatin if you are pregnant, planning to become pregnant, or breastfeeding. They can assess your individual situation and provide appropriate guidance. 

Guidance 

In some cases, Rasuva 10 should not be consumed.  These are:

• If you have liver issues,.
• if pregnant
• If the possibility of pregnancy exists,
• Breastfeeding mothers

Avoid it in these conditions. In cases of special need, it can be consumed as per the doctor’s advice.

Effects of overdosing Rosuva 10

While there is limited information on specific overdose cases with Rosuvastatin 10 mg, it is important to seek medical attention immediately if you suspect an overdose.

Potential Symptoms of Overdose:

• Gastrointestinal symptoms: Nausea, vomiting, abdominal pain  
• Muscle pain, tenderness, or weakness: This may be a sign of rhabdomyolysis, a serious condition that can lead to kidney damage.  
• Liver problems: Symptoms may include jaundice, dark urine, and light-colored stools.
• Neurological symptoms: Headache, dizziness, confusion

Treatment:

• If you suspect an overdose of Rosuvastatin, seek medical attention immediately.
• Treatment may involve supportive measures, such as monitoring vital signs and managing any symptoms that may arise.
• There is no specific antidote for Rosuvastatin overdose.

Remember, it is crucial to contact a healthcare professional or emergency services immediately if you suspect an overdose of any medication. 

Therapeutic classes Rosuva 10 

Therapeutic classes are: Other Anti-anginal & Anti-ischaemic drugs, Statins

Warning | Rosuva 10   

Rosuvastatin is contraindicated if-

• Known hypersensitivity to product components
• Liver disease, which may include unexplained persistent elevations in hepatic transaminase levels
• Pregnant women and women who may become pregnant
• Nursing mothers

Chemical composition:

Chemical Formula: C22H28FN3O6S

Chemical Stucture: 

Storage Conditions 

 Storage Instructions for Rosuvastatin 10 mg: Store below 30°C temperature. Protect from light and moisture. Keep out of the reach of children. By following these storage guidelines, you can help ensure the effectiveness and safety of your Rosuvastatin medication.

***Special announcement

Although we have carefully gathered the information from various sources, you should not use it as a substitute for medical advice. Always consult a doctor before using any medication. Our source-based information cannot be guaranteed to be effective or useful. Therefore, we cannot be held responsible for any side effects that may occur after taking the medicine based on the information mentioned above.

• This information is for general information only and is in no way a substitute for medical advice.

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Rosuva 10: FAQs   

What is Rosuva 10 mg Tablet used for?

Rosuva 10 mg Tablet is primarily used to lower cholesterol and triglyceride levels in the body, helping to manage conditions like hyperlipidemia and prevent stroke.

How does Rosuva 10 mg Tablet work?

Rosuva works by inhibiting the HMG-CoA reductase enzyme, which plays a key role in cholesterol production in the liver.

What are the common side effects of Rosuva 10 mg Tablet?

Common side effects include muscle pain, weakness, headache, and abdominal pain.

Can I take Rosuva 10 mg Tablet if I have diabetes?

Yes, but it’s essential to monitor your blood sugar levels regularly, as Rosuva may increase blood sugar levels.

Is it safe to drink alcohol while taking Rosuva 10 mg Tablet?

No, it is advisable to avoid alcohol during treatment with Rosuva, as it may increase the risk of liver problems.

How should I take Rosuva 10 mg Tablet?

Rosuva 10 mg Tablet should be taken once a day, with or without food, as directed by your doctor.

Can Rosuva 10 mg Tablet cause weight gain?

Weight gain is a rare side effect; if you experience this, consult your doctor for further evaluation.

What should I do if I miss a dose of Rosuva 10 mg Tablet?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one and resume your regular schedule.

Are there any dietary restrictions while taking Rosuva 10 mg Tablet?

Yes, avoid high-calorie and junk foods, as a low-cholesterol diet is recommended during treatment.

Can Rosuva 10 mg Tablet lead to muscle problems?

Yes, muscle pain or weakness can occur; consult your doctor if you experience significant discomfort.

How long should I take Rosuva 10 mg Tablet?

Continue taking Rosuva as long as your doctor recommends and until you see improvement in your condition.

Does Rosuva 10 mg Tablet affect liver function?

Yes, it can affect liver function, so your doctor may monitor liver enzymes during treatment.

Can Rosuva 10 mg Tablet cause memory loss?

Memory loss is a rare side effect; if you notice this, stop taking the medication and contact your doctor.

Should Rosuva 10 mg Tablet be taken at night?

It’s not mandatory; you can take it in the morning or evening, but consistency in timing is essential.

Is Rosuva 10 mg Tablet suitable during pregnancy or breastfeeding?

No, Rosuva is not recommended for pregnant or breastfeeding women. Always consult your doctor for safer alternatives. 

reference

Company: http://www.squarepharma.com.bd/product-details.php?pid=197   

USP: https://store.usp.org/product/1365000 

Generic: https://en.wikipedia.org/wiki/Rosuvastatin