Rosu 5 mg. Tablets || Price, Generic, Dosage, and all information 

• Generic Name: Rosuvastatin
• Manufacturing Company:  Popular Pharmaceuticals Ltd.

The price Rosu 5mg  

• Per piece: 12.50 Tk
• Strip: 125 Tk (10 tablets)
• Box: 375 Tk (10*3 Tablets)

 

Rosu 5 mg Tablet is a medication belonging to the HMG-CoA reductase inhibitor class, commonly known as statins. It is primarily used to lower cholesterol and triglyceride levels in the body, making it effective in managing conditions such as hyperlipidaemia, hypertriglyceridemia, and type 3 hyperlipoproteinemia. Additionally, it helps reduce the risk of stroke in patients with high cholesterol levels. The tablet works by reducing “bad” cholesterol (LDL) and triglycerides, while raising “good” cholesterol (HDL) when combined with a healthy lifestyle, including a low-fat diet and regular exercise. Common side effects of Rosu 5 mg Tablet include muscle pain, weakness, headache, and abdominal pain. In rare cases, it may cause memory loss or elevate blood sugar levels, particularly in patients already at risk for diabetes. It is generally safe to use under a doctor’s supervision, but alcohol should be avoided as it can increase the risk of liver damage and raise triglyceride levels. Regular monitoring of liver function and blood sugar levels is recommended, especially for patients with underlying health conditions. Pregnant or breastfeeding women should not use Rosu 5 mg Tablet.

Alternative medicine 

There are many alternative medicines of Rasu 5 available in the market from different companies, some of them are:  

 

Sl:	Alternative	Company	Price
1.	Rovast 10	Healthcare Pharmaceuticals Ltd	10 Tk
2.	Rosuva 10	Square Pharmaceuticals Ltd	10 Tk
3.	Rocovas 10	Incepta Pharmaceuticals Ltd	10 Tk
4.	Rostatin 10	Drug International Ltd	11.20 Tk
5.	RTV	Delta Pharma Ltd	5 Tk

 

Indications | Rosu 5 mg 

Rosu 5 mg Tablet is primarily indicated for the following conditions:

• Hyperlipidemia: Rosu 5 mg is prescribed to lower high cholesterol levels, especially low-density lipoprotein (LDL) cholesterol, which is considered “bad” cholesterol.
• Hypertriglyceridemia: It helps in reducing elevated triglycerides, a type of fat in the blood, which can increase the risk of heart disease.
• Prevention of Cardiovascular Disease: Rosu 5 mg is used to reduce the risk of heart attacks, strokes, and other heart-related conditions in patients with risk factors such as high cholesterol or diabetes.
• Familial Hypercholesterolemia: This medication is also used for patients with heterozygous or homozygous familial hypercholesterolemia, a genetic disorder that leads to extremely high cholesterol levels.
• Type 3 Hyperlipoproteinemia: Rosu 5 mg is indicated for patients suffering from this condition, which involves abnormal levels of lipoproteins in the blood.

Rosu 5 mg works best when combined with a healthy diet, regular exercise, and lifestyle changes to manage cholesterol levels effectively. 

Pharmacology  

Rosuvastatin is a selective, competitive inhibitor of HMG-CoA reductase, the enzyme responsible for the rate-limiting step in cholesterol synthesis. It works by preventing the conversion of 3-hydroxy-3-methyl-glutaryl coenzyme A to mevalonate, a precursor of cholesterol. Rosuvastatin modifies lipid levels through two main mechanisms: first, it increases the number of LDL receptors in the liver, which enhances the uptake and breakdown of LDL (low-density lipoprotein). Second, it inhibits the liver’s production of VLDL (very low-density lipoprotein), reducing both VLDL and LDL particles in the bloodstream.

Dosage and Administration  

Heterozygous Familial Hypercholesterolemia in Pediatric Patients (10-17 years):

• Usual dose range: 5-20 mg/day.
• Maximum dose: 20 mg/day (doses above 20 mg not studied in this group).
• Adjust doses every 4 weeks or more based on therapy goals.

Very High Cholesterol and High Risk of MI or Stroke:

• Recommended dose: 40 mg once daily.

Homozygous Familial Hypercholesterolemia:

• Starting dose: 20 mg once daily.
• Adjust treatment based on preapheresis LDL-C levels.

Dosage for Asian Patients:

• Initiate with 5 mg once daily.

Use with Cyclosporine:

• Limit Rosuvastatin dose to 5 mg once daily.

Use with Lopinavir/Ritonavir or Atazanavir/Ritonavir:

• Limit Rosuvastatin dose to 10 mg once daily.

Concomitant Lipid-Lowering Therapy:

• Increased risk of muscle effects when combined with Niacin or Fenofibrate.
• Reduce Rosuvastatin dose in these cases.

Combination with Gemfibrozil:

• Avoid use due to increased Rosuvastatin exposure.
• If necessary, limit Rosuvastatin dose to 10 mg once daily.

Severe Renal Impairment (ClCr <30 mL/min/1.73 m²):

• Start at 5 mg once daily.
• Do not exceed 10 mg daily.

This list provides a simplified overview of the dosage and administration recommendations for Rosuvastatin under various conditions. 

Drug interactions Rosu 5

Rosu 5 mg (Rosuvastatin) has several important drug interactions to be aware of. When taken with Cyclosporine, the concentration of Rosuvastatin increases significantly, requiring the dose to be limited to 5 mg once daily. Similarly, co-administration with Lopinavir/Ritonavir or Atazanavir/Ritonavir boosts Rosuvastatin levels, so the maximum dose should not exceed 10 mg per day. The combination of Rosuvastatin with Gemfibrozil increases the risk of muscle-related side effects, so it’s advisable to avoid using them together, or if necessary, restrict Rosuvastatin to 10 mg daily. Additionally, taking Rosuvastatin with Niacin or Fenofibrate can elevate the risk of muscle problems, warranting dosage adjustments.

Rosuvastatin’s absorption is also affected by antacids containing aluminum or magnesium hydroxide, so it should be taken at least two hours after consuming such antacids. When used with Warfarin, Rosuvastatin may enhance its effects, increasing the risk of bleeding, and necessitating regular monitoring of INR (International Normalized Ratio). Co-administration with Erythromycin can reduce Rosuvastatin concentration, requiring medical consultation. Finally, the use of Fusidic Acid alongside Rosuvastatin increases the risk of muscle issues, making it essential to avoid this combination or closely monitor the patient. 

Side effects Rosu 5  

Rosu 5 mg (Rosuvastatin) may cause a range of side effects, though not everyone experiences them. Common side effects include muscle pain, weakness, and headache. Some individuals may also experience abdominal pain, nausea, and constipation. In rare cases, Rosuvastatin can cause liver problems, leading to symptoms like dark urine, yellowing of the skin or eyes (jaundice), and upper stomach pain.

Other less frequent side effects include dizziness, fatigue, and difficulty sleeping. Some patients might notice increased blood sugar levels, especially if they are at risk for diabetes. Memory loss or confusion has been reported, but these are uncommon. Rare but serious side effects include severe muscle damage (rhabdomyolysis) and kidney problems, especially when taken with certain other medications. It’s essential to consult a doctor if any unusual or persistent symptoms occur during treatment with Rosu 5 mg. 

Use during pregnancy and lactation 

Rosuvastatin should only be prescribed to women of childbearing age if they are highly unlikely to become pregnant and have been informed about the potential risks. If a patient becomes pregnant while taking Rosuvastatin, the treatment should be stopped immediately. It is not known if Rosuvastatin is excreted in human breast milk, although a small amount of a similar drug from the same class has been found to pass into breast milk. Therefore, caution is advised when administering this medication to nursing mothers. 

Guidance 

In certain cases, you should avoid consuming Rosu 5.  These are: if you have liver problems, if you are pregnant, if you are likely to become pregnant, and if you are breastfeeding.

Avoid it in these conditions. Consume it according to the doctor’s advice in cases of special need.

Effects of overdosing Rosu 5

In the case of an overdose of Rosuvastatin, there is no specific treatment available. Patients should be managed symptomatically, and supportive measures should be implemented as needed. It is important to note that hemodialysis does not significantly improve the clearance of Rosuvastatin from the body.

Therapeutic classes Rosu 5 

Therapeutic classes are: Other Anti-anginal & Anti-ischaemic drugs, Statins

Warning | Rosu 5   

In some cases, Rosu 5 requires caution. Do not take this medicine if you are allergic to any of its ingredients or have liver problems, especially high liver enzyme levels.  Rosu 5 mg is also not safe for pregnant women and lactating mothers. 

Chemical composition:

Chemical Formula: C22H28FN3O6S

Chemical Stucture: 

Storage Conditions 

 

***Special announcement

We have collected the mentioned information from various sources with caution, but they are in no way a substitute for doctors, so consult doctors for any medicine to use. We cannot guarantee the effectiveness and usefulness of the information we collect from various sources. Therefore, we cannot be held responsible for any side effects that may occur after taking the medicine, due to the information mentioned above.

• This information is for general information only and is in no way a substitute for medical advice.

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Red 5mg: FAQs

What is Rosu 5 mg Tablet used for? 

Rosu 5 mg Tablet is used to lower high cholesterol and triglycerides, helping to prevent heart disease and stroke.

How does Rosu 5 mg Tablet work? 

Rosu 5 mg works by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol production, thereby lowering “bad” cholesterol (LDL) and increasing “good” cholesterol (HDL).

What are the common side effects of Rosu 5 mg Tablet? 

Common side effects include muscle pain, weakness, headache, nausea, and abdominal discomfort.

Can I take Rosu 5 mg Tablet with other medications? 

Some medications may interact with Rosu 5 mg, so it’s essential to inform your doctor about all drugs you’re taking.

How long should I take Rosu 5 mg Tablet? 

The duration of use depends on your medical condition; follow your doctor’s instructions for proper treatment.

Does Rosu 5 mg Tablet cause weight gain? 

Weight gain is a rare side effect of Rosu 5 mg. Consult your doctor if you notice significant weight changes.

Is Rosu 5 mg Tablet safe during pregnancy? 

Rosu 5 mg is not recommended during pregnancy as it can harm the fetus. Discuss alternatives with your doctor.

Can I consume alcohol while taking Rosu 5 mg Tablet? 

Avoid alcohol, as it may increase the risk of liver problems and affect cholesterol management.

When is the best time to take Rosu 5 mg Tablet?

 Rosu 5 mg can be taken at any time of the day, but it’s important to take it consistently at the same time daily.

Does Rosu 5 mg Tablet help with weight loss? 

Rosu 5 mg is not a weight loss drug but helps in managing cholesterol, which can aid overall health.

Can Rosu 5 mg Tablet cause muscle pain? 

Yes, muscle pain is a common side effect of Rosu 5 mg. If the pain is severe, consult your doctor.

Is Rosu 5 mg Tablet safe for long-term use? 

Rosu 5 mg is generally safe for long-term use under a doctor’s supervision, with regular monitoring of liver and kidney functions.

Can Rosu 5 mg Tablet cause diabetes? 

While Rosu 5 mg does not cause diabetes, it may increase blood sugar levels in some individuals already at risk.

What should I avoid while taking Rosu 5 mg Tablet? 

Avoid high-fat foods, alcohol, and grapefruit juice, which can interfere with the medication’s effectiveness.

Can Rosu 5 mg Tablet be taken with food? 

Rosu 5 mg can be taken with or without food, but if you experience stomach upset, it may help to take it with food.

reference

• Company: https://www.popular-pharma.com/products/302   
• USP: https://store.usp.org/product/1365000 
• Generic: https://en.wikipedia.org/wiki/Rosuvastatin