Flexi 100 mg. Tablets  || Price, Generic, Dosage, and all information 

• Generic name:  Aceclofenac 
• Manufacturing Company:  Square Pharmaceuticals Ltd.

The price Flexi 100mg  

• Per piece: 5 Tk 
• Page: 50 Tk(10 tablets)
• Box: 50 Tk(10*10 Tablets)

Flexi 100 is a non-steroidal anti-inflammatory drug (NSAID) indicated for the relief of pain and inflammation associated with various conditions, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothaches, trauma, and lumbago. The active ingredient, Aceclofenac, possesses potent analgesic and anti-inflammatory properties by effectively inhibiting the enzyme cyclooxygenase, which plays a crucial role in the production of prostaglandins. Available in both extended-release and film-coated tablet forms, Flexi 100 is designed for convenient dosing, with the recommended dosage tailored to individual needs based on physician advice. While it provides significant benefits in managing pain and inflammation, caution is advised in certain populations, including those with specific medical conditions. Overall, Flexi 100 represents a valuable option for patients seeking relief from inflammatory pain.

Alternative Medicine 

There are many Aceclofenac generic alternatives to Flexi 100 from different companies in the market, they are:  

Sl:	alternative	Manufacturing	Price (per piece)
1.	Mervan 100mg	Aristopharma Ltd.	7 Tk
2.	Reservix 100mg	Incepta Pharmaceuticals Limited.	6 Tk
3.	Zoflin 100mg	Beximco Pharmaceuticals Limited.	4 Tk
4.	Avenac 100mg	Radiant Pharmaceuticals Ltd.	5 Tk
5.	Movex 100mg	Opsonin Pharmaceuticals Ltd.	5 Tk

Indications | Flexi 100 

Flexi 100 is indicated for the relief of pain and inflammation associated with the following conditions:

• Osteoarthritis: A degenerative joint disease characterized by the breakdown of cartilage, leading to pain and stiffness.
• Rheumatoid Arthritis: An autoimmune disorder that causes chronic inflammation of the joints, resulting in pain, swelling, and potential joint damage.
• Ankylosing Spondylitis: A type of arthritis that primarily affects the spine, leading to inflammation, pain, and stiffness.
• Toothache: Pain resulting from dental issues or procedures.
• Trauma: Pain and inflammation resulting from injuries or accidents.
• Lumbago: Lower back pain, which may arise from various causes, including muscle strain or degenerative disc disease.

Note: Always consult a registered healthcare provider before using this medication.

Pharmacology 

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) known for its analgesic and anti-inflammatory effects. It effectively inhibits the enzyme cyclooxygenase (COX), which plays a crucial role in the synthesis of prostaglandins—substances that mediate pain and inflammation. Following oral administration, Aceclofenac is rapidly and fully absorbed in its unchanged form, ensuring prompt therapeutic action.

Dosage and Administration  

Extended Release Tablet:

• The recommended dose for adults is one 200 mg Aceclofenac tablet daily, or as directed by a healthcare provider.

Film-Coated Tablet:

• The recommended dose for adults is 100 mg taken twice daily, or as prescribed by a physician.

Administration Guidelines:

• Take the tablets with a sufficient amount of water.
• It is advisable to follow the dosage instructions provided by your healthcare provider for optimal results.

Note: Always consult with a registered healthcare professional before starting any medication.

Drug interactions

While significant drug interactions with Flexi 100 (Aceclofenac) have not been widely reported, it is important to exercise caution when using it alongside certain medications. For instance, Flexi 100 may increase the plasma concentration of lithium and digoxin, potentially leading to toxicity. Additionally, the efficacy of diuretics may be affected, which could result in fluid retention. When combined with anticoagulants, Flexi 100 may enhance their effects, thereby increasing the risk of bleeding. Furthermore, concurrent use with methotrexate may elevate its plasma levels, necessitating careful monitoring. It is crucial to inform your healthcare provider about all medications you are currently taking to minimize the risk of adverse interactions.

Side Effects  

Flexi 100 (Aceclofenac) is generally well tolerated for both short-term and long-term treatment. However, some individuals may experience side effects. The most common side effects include headache and diarrhea. Less frequently reported side effects may include abdominal pain, flatulence, rash, insomnia, and hyperglycemia. It is important to monitor for any adverse reactions, especially if you have underlying health conditions. If you experience severe side effects or signs of an allergic reaction, it is advisable to seek medical attention promptly. Always consult with your healthcare provider for any concerns regarding side effects while using this medication.

Use during pregnancy and lactation 

The use of Flexi 100 (Aceclofenac) is generally advised against during pregnancy and lactation unless the potential benefits to the mother outweigh the possible risks to the fetus or nursing infant. There is limited data on the safety of Aceclofenac in pregnant women, and animal studies do not always predict human responses. Therefore, it is essential to consult with a healthcare provider before using Flexi 100 if you are pregnant or breastfeeding. The healthcare provider will evaluate your specific situation and determine the best course of action to ensure both maternal and fetal safety.

Guidance 

Caution: Use carefully if you have peptic ulcers, gastrointestinal bleeding, or severe hepatic, cardiac, or renal impairment.

Adverse Reactions: Report any dizziness or urticaria to your healthcare provider.

Dosage: Follow the prescribed dosage and duration strictly.

Monitoring: Regular monitoring is advised for chronic conditions or polypharmacy.

Consultation: Always consult your healthcare provider before any changes to your medication.

Effects of overdose

In the event of an overdose of Flexi 100 (Aceclofenac), symptoms may vary in severity and can include gastrointestinal distress such as nausea, vomiting, and abdominal pain. Additionally, dizziness, headache, and drowsiness may occur. In severe cases, an overdose can lead to renal impairment and gastrointestinal bleeding.

If an overdose is suspected, it is crucial to seek immediate medical attention. There is no specific antidote for Aceclofenac; treatment is primarily supportive and symptomatic. Always adhere to the prescribed dosage to minimize the risk of overdosing, and consult your healthcare provider for any concerns regarding medication use.

Therapeutic classes 

Therapeutic classes are:  Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Warning |  Flexi 100

• Gastrointestinal Risks: This condition may increase the risk of bleeding, ulceration, or perforation, especially in those with a history of such conditions.
• Cardiovascular Effects: Prolonged use may raise the risk of serious cardiovascular events; use cautiously in patients with cardiovascular issues.
• Renal Impairment: Patients with pre-existing renal conditions should exercise caution as it may exacerbate their kidney function.
• Hepatic Caution: Monitor liver function in patients with liver disease or on long-term therapy.
• Allergic Reactions: If you notice any signs of an allergic reaction, discontinue use immediately.
• Pregnancy and Lactation: Avoid during pregnancy and breastfeeding unless benefits outweigh risks; consult your healthcare provider.

For any concerns about Flexi 100, always consult your healthcare provider.

Chemical Composition

Chemical Formula: C16H13Cl2NO4

Chemical Stucture: 

Terms and Conditions 

***Special announcement

Although we have carefully gathered the information from various sources, you should not use it as a substitute for medical advice. Always consult a doctor before using any medication. We cannot guarantee the effectiveness or usefulness of our source-based information. Therefore, the above-mentioned information does not hold us responsible for any side effects that may occur after taking the medicine.

• This information is for general information only and is in no way a substitute for medical advice.

Read More:

• Opton 20 mg Tablet Price – Guidelines – Doses
• Pantid 20 mg Tablet Price || Price, Generic, Dosage, and all information 

Flexi 100 mg. – FAQs  

What is Flexi 100 mg used for?

Patients with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma, and lumbago use Flexi 100 mg to relieve pain and inflammation.

How does Flexi 100 mg work?

It works as a non-steroidal anti-inflammatory drug (NSAID) by inhibiting the enzyme cyclooxygenase, which reduces the production of prostaglandins that cause pain and inflammation.

What is the recommended dosage for Flexi 100 mg?

The typical dose is 100 mg, taken twice daily or as directed by your physician.

On an empty stomach, can I take Flexi 100 mg?

The general recommendation is to take Flexi 100 mg with food to minimize gastrointestinal irritation.

Does Flexi 100 mg have any common side effects?

Common side effects include headache, diarrhea, abdominal pain, and rash.

Is Flexi 100 mg safe for long-term use?

While it can be used long-term, regular monitoring is recommended to assess for any potential adverse effects, particularly gastrointestinal or renal issues.

Can I take Flexi 100 mg with other medications?

You should consult your healthcare provider, as it may interact with medications like lithium, diuretics, anticoagulants, and methotrexate.

What should I do if I miss a dose of Flexi 100 mg?

If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip the missed dose and continue with your regular schedule.

Is Flexi 100 mg safe during pregnancy?

Use of Flexi 100 mg during pregnancy is generally advised against unless absolutely necessary. Consult your healthcare provider for guidance.

Can I drink alcohol while taking Flexi 100 mg?

It is advisable to limit or avoid alcohol, as it can increase the risk of gastrointestinal side effects.

How should I store Flexi 100 mg?

Store Flexi 100 mg in a cool, dry place away from light and out of reach of children.

What should I do in case of an overdose?

If an overdose is suspected, seek immediate medical attention. Symptoms may include gastrointestinal distress and renal impairment.

Is Flexi 100 mg suitable for children?

There is limited clinical data on the use of Flexi 100 mg in children; consult your healthcare provider for advice.

Can I take Flexi 100 mg if I have a history of allergies?

If you have a known hypersensitivity to Aceclofenac or NSAIDs, you should avoid using Flexi 100 mg and consult your healthcare provider.

What should I do if I experience side effects?

If you experience severe side effects or signs of an allergic reaction, discontinue use and consult your healthcare provider immediately.

reference

Company: https://www.squarepharma.com.bd/product-details.php?pid=202    

BP: https://labmix24.com/en/pharmaceutical-reference-standards/british-pharmacopoeia 

Generic:    https://en.wikipedia.org/wiki/Aceclofenac