- Generic Name: Amlodipine Besilate
- Manufacturing Company: ACME Laboratories Ltd.
The price of Amlopin 5
- Per piece: 5.01 Tk
- Strip: 50.10 Tk(10 tablets)
- Box: 250.50 Tk (5*10 Tablets)
Amlopin 5 mg is a medication produced by ACME Laboratories Ltd., designed primarily for the management of essential hypertension and various forms of angina pectoris, including chronic stable angina and vasospastic angina. Each tablet contains 5 mg of Amlodipine Besilate, a dihydropyridine calcium-channel blocker known for its long duration of action. Amlopin works by inducing vasodilation, leading to reduced peripheral resistance, lower blood pressure, and enhanced coronary blood flow, which collectively improve myocardial oxygen supply and cardiac output. Available at a unit price of ৳ 5.01 and packaged in strips, Amlopin is often prescribed as a monotherapy or in combination with other antihypertensive or antianginal agents. As with all medications, it is essential to use Amlopin under the guidance of a registered healthcare professional.
Alternative medicine
There are many alternatives to Amlopin 5 available in the market from different companies, some of them are:
| SL: | Alternative medicine | Manufacturing | Price |
| 1. | Amlotab 5 | Incepta Pharmaceuticals Ltd. | 5 Tk |
| 2. | Camlodin 5 | Square Pharmaceuticals PLC. | 5 Tk |
| 3. | Amlotab 5 | Incepta Pharmaceuticals Ltd. | 5 Tk |
| 4. | Cardiphin 5 | Renata Limited. | 5 Tk |
| 5. | Amlocard 5 | Drug International Ltd. | 5 Tk |
Indications | Amlopin 5
Indications for Amlopin 5 mg:
- Essential Hypertension: Amlopin is effective as a monotherapy for treating hypertension. It may also be used in combination with other antihypertensive medications to achieve better control of blood pressure.
- Chronic Stable Angina Pectoris: Amlopin is indicated for the treatment of chronic stable angina pectoris. It can be used alone or in conjunction with other antianginal agents to relieve symptoms and improve exercise tolerance.
- Vasospastic Angina: Amlopin is recommended for patients with confirmed or suspected vasospastic angina. It can be used as monotherapy or in combination with other antianginal drugs to manage symptoms effectively.
Note: Amlopin should be taken as prescribed by a registered healthcare professional.
Pharmacology Amlopin 5
Amlopin contains amlodipine besilate, a dihydropyridine calcium-channel blocker. It works primarily by inhibiting calcium ions from entering vascular smooth muscle and cardiac muscle. This action leads to vasodilation, resulting in reduced peripheral resistance and blood pressure, which alleviates the workload on the heart. Amlodipine’s effects include; Vasodilation: The drug relaxes blood vessels, leading to a decrease in blood pressure and afterload. Increased Coronary Blood Flow: Amlopin enhances blood flow to the heart muscle, improving oxygen delivery. Cardiac Output: It increases cardiac output while maintaining a reflex increase in heart rate. Due to its long duration of action, Amlopin is effective in managing hypertension and angina pectoris, providing sustained relief and improving patient outcomes.
Dosage and Administration
Dosage and Administration of Amlopin 5 mg:
- Hypertension:
- Usual Dose: 5 mg once daily.
- Maximum Dose: 10 mg once daily.
- Special Populations: Elderly patients or those with hepatic insufficiency may start with 2.5 mg once daily.
- Angina (Chronic Stable or Vasospastic):
- Recommended Dose: 5 to 10 mg once daily, with 5 mg recommended for elderly patients or those with hepatic insufficiency. Most patients require 10 mg for effective management.
- Administration: Amlopin can be taken without regard to meals, making it convenient for daily use.
Note: Always consult a registered healthcare professional for personalized dosing recommendations.
Drug interactions Amlopin 5
Amlopin 5 mg may have some drug interactions that require consideration. Caution is advised when combining Amlopin with beta-blockers, particularly in patients with significantly impaired cardiac left ventricular function, as potentially hazardous interactions could arise. However, studies have shown no significant interactions between Amlopin and other medications like Digoxin and Cimetidine, indicating that these drugs can be used together without concern. Additionally, Amlopin does not significantly alter the effects of Warfarin on prothrombin time, which is beneficial for patients requiring anticoagulation therapy. Importantly, the absorption of Amlopin is not affected by food, allowing for flexible administration without the need to coordinate with meals. It is always essential to consult a healthcare professional before starting any new medications to ensure safety and effectiveness.
Side effects Amlopin 5
Amlopin 5 is a medication prescribed to treat high blood pressure. Like any medication, it can have side effects. While not everyone experiences them, it’s essential to be aware of potential risks. Common side effects include dizziness, headache, fatigue, nausea, cough, muscle cramps, and swelling in the ankles or feet. Less common side effects may include rapid heartbeat, chest pain, difficulty breathing, rash, tingling in the hands or feet, erectile dysfunction, and changes in taste. If you experience any of these side effects, especially if they become severe, it’s crucial to contact your doctor. Please note that this is not an exhaustive list of all possible side effects. For a complete list, refer to the medication information provided by your pharmacist or doctor. It’s important to follow your doctor’s instructions regarding dosage and usage. If you have concerns about Amlopin 5 or its potential side effects, discuss them with your healthcare provider.
Use during pregnancy and lactation
Amlopin (Amlodipine) falls under Pregnancy Category C, indicating that there are no adequate and well-controlled studies in pregnant women. It should only be used during pregnancy if the potential benefits justify the risks to the fetus. As for lactation, it is unclear whether Amlodipine is excreted in human breast milk. Due to the lack of definitive information, it is recommended to discontinue breastfeeding while administering Amlopin. Therefore, healthcare providers should carefully evaluate the necessity of Amlopin for pregnant or breastfeeding patients and consider alternative treatments when possible.
Effects of overdosing Amlopin 5
Overdosage of Amlopin (Amlodipine) may lead to significant adverse effects, primarily due to excessive peripheral vasodilation. Symptoms can include marked and prolonged systemic hypotension, which may progress to shock and potentially fatal outcomes. Patients might experience reflex tachycardia as a compensatory response. In managing Amlodipine overdose, immediate cardiovascular support is essential, including close monitoring of cardiac and respiratory functions. Elevating the extremities and maintaining adequate circulating fluid volume and urine output are crucial. A vasoconstrictor may be administered to restore vascular tone and blood pressure if appropriate. Intravenous calcium gluconate can help reverse the effects of calcium channel blockade. Gastric lavage might be considered in some cases, and the use of activated charcoal within two hours of ingestion can reduce the absorption of Amlodipine. Since Amlodipine is highly protein-bound, dialysis is not likely to be effective in removing the drug from the system.
Therapeutic classes Amlopin 5
Therapeutic classes are: Calcium-channel blockers
Usage Precautions
Do not take Amlodipine 5 if you are allergic to Amlodipine. And do not take Amlopin 5 if you have severe heart disease (eg, heart failure, aortic stenosis).
Be careful in other cases:
- If you have kidney or liver problems,
- While pregnant or breastfeeding
- If you regularly take any other medication,
- Avoid drinking alcohol while taking Amlopin 5.
- Keep it out of children’s reach.
Chemical composition Amlopin 5
Chemical Formula: C20H25ClN2O5
Chemical Stucture:
Storage Conditions
Keep all medicines out of reach of children. Store in a cool & dry place, protected from light.
***Special announcement
Although we have carefully gathered the information from various sources, you should not use it as a substitute for medical advice. Always consult a doctor before using any medication. We cannot guarantee the effectiveness and usefulness of the information we collect from various sources. Therefore, we cannot be held responsible for any side effects that may occur after taking the medicine, due to the information mentioned above.
- This information is for general information only and is in no way a substitute for medical advice.
- Consult your doctor before consuming.
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Answers to frequent questions about Amlopin 5
What is Amlopin 5 used for?
Amlopin 5 is primarily used to treat essential hypertension (high blood pressure) and angina pectoris (chest pain). It can be used alone or in combination with other antihypertensive or antianginal medications.
How does Amlopin work?
Amlopin is a calcium channel blocker that relaxes blood vessels, leading to vasodilation. This helps lower blood pressure and reduces the heart’s workload, improving blood flow to the heart.
What is the usual dosage of Amlopin?
The typical starting dose for adults is 5 mg once daily. Depending on the patient’s response, the dose may be increased to a maximum of 10 mg once daily.
Can Amlopin be taken with food?
Yes, Amlopin can be taken with or without food, as food does not affect the absorption of the medication.
Are there any significant drug interactions with Amlopin?
Amlopin may interact with beta-blockers, digoxin, and cimetidine, among others. It is important to consult a healthcare provider before combining Amlopin with other medications.
What are the common side effects of Amlopin?
Common side effects include dizziness, flushing, headache, peripheral edema (swelling), and hypotension (low blood pressure). Most side effects are mild and temporary.
Is Amlopin safe to use during pregnancy?
Amlopin is classified as pregnancy category C, meaning it should only be used during pregnancy if the potential benefits outweigh the risks. Consult a doctor for guidance.
Can I take Amlopin while breastfeeding?
It is unknown whether Amlopin is excreted in breast milk. Therefore, nursing should be discontinued while taking Amlopin, unless advised otherwise by a healthcare provider.
What should I do if I miss a dose of Amlopin?
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
What should I do in case of an overdose?
In case of an overdose, seek immediate medical attention. Symptoms may include severe hypotension and reflex tachycardia. Treatment may involve cardiovascular support and other interventions.
Can Amlopin be used in elderly patients?
Yes, Amlopin can be used in elderly patients, but it is essential to start with a lower dose (2.5 mg) and monitor for effectiveness and side effects.
Are there any contraindications for taking Amlopin?
Amlopin should not be used in patients with a known hypersensitivity to dihydropyridine derivatives or in pregnant women without medical advice.
Can children use Amlopin?
Amlopin is approved for children aged 6 to 17 years, with a typical starting dose of 2.5 mg daily, which may be increased if necessary. Consult a pediatrician for specific guidance.
How should Amlopin be stored?
Amlopin should be stored in a cool, dry place away from light and out of reach of children.
What should I do if I experience severe side effects?
If you experience severe side effects, such as swelling, difficulty breathing, or severe dizziness, seek immediate medical attention and inform your doctor about your symptoms.